Immunomodulatory and antiviral effects of Lycium barbarum glycopeptide on influenza a virus infectionArticle Published on 2023-03-012023-06-24 Journal: Microbial pathogenesis [Category] 신종인플루엔자, [키워드] antivirus immunomodulation influenza A virus Lycium barbarum glycopeptide macrophage polarization Viral pneumonia. [DOI] 10.1016/j.micpath.2023.106030 PMC 바로가기
Folic acid: a potential inhibitor against SARS-CoV-2 nucleocapsid protein엽산: SARS-CoV-2 뉴클레오캡시드 단백질에 대한 잠재적 억제제Article Published on 2022-12-012022-09-11 Journal: Pharmaceutical Biology [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료법, [키워드] analysed Analysis antagonist antiviral effects antivirus association cellular Chinese Chinese medicine Compound Concentration coronavirus disease Coronavirus disease 2019 COVID-19 Data analysis docking drug target experiment Folic acid Genes global pandemic Host hub genes identify inhibit inhibition inhibitor involved material mCherry mCherry expression mechanism molecular molecular docking network pharmacology Network pharmacology. Nucleocapsid phosphoprotein Phosphoprotein Protein Regulatory RNA interference RNAi SARS-CoV-2 SARS-CoV-2 N SARS-CoV-2 nucleocapsid screened shown target targets therapeutic target Traditional Traditional Chinese medicine virus [DOI] 10.1080/13880209.2022.2063341 PMC 바로가기 [Article Type] Article
Glycine Nano-Selenium Enhances Immunoglobulin and Cytokine Production in Mice Immunized with H9N2 Avian Influenza Virus VaccineArticle Published on 2022-07-182023-06-22 Journal: International Journal of Molecular Sciences [Category] 조류인플루엔자, [키워드] antivirus Immunity immunization Nano-Selenium trace element. [DOI] 10.3390/ijms23147914 PMC 바로가기
Aprotinin treatment against SARS-CoV-2: A randomized phase III study to evaluate the safety and efficacy of a pan-protease inhibitor for moderate COVID-19SARS-CoV-2에 대한 아프로티닌 치료: 중등도 COVID-19에 대한 범프로테아제 억제제의 안전성과 효능을 평가하기 위한 무작위 3상 연구Clinical Trial Published on 2022-06-012022-09-11 Journal: European Journal of Clinical Investigation [Category] COVID19(2023년), SARS, 임상, 치료제, [키워드] ACE2 addition administration Adverse reaction Adverse reactions anti-inflammatory properties anti-inflammatory property antiviral drug antivirus Aprotinin cleave Clinical outcome clinical trial Composite Contact COVID-19 death discharge double-blind Efficacy evaluate follow-up period furin had no hospital Hospital admission Hospital stay Hospitalization hospitalized patient hospitalized patients host protease host proteases human respiratory viruses ICU admission IMPROVE incidence inhalation therapy inhibiting inhibitor Innate immunity less mechanism Moderate COVID-19 multicentre outcome oxygen Oxygen therapy parameter patients with COVID-19 performed placebo group Pneumonia profiles Protease inhibitor protease inhibitor. Randomized randomized trial required respiratory viruses resulting Safe Safety SARS-CoV-2 SARS-CoV-2 virus secondary endpoint Secondary endpoints Side effects significant difference significant differences Spanish Spike protein standard treatment the placebo group Treatment with COVID-19 [DOI] 10.1111/eci.13776 PMC 바로가기 [Article Type] Clinical Trial
A Therapeutically Active Minibody Exhibits an Antiviral Activity in Oseltamivir-Resistant Influenza-Infected Mice via Direct Hydrolysis of Viral RNAsArticle Published on 2022-05-212023-06-23 Journal: Viruses [Category] 신종인플루엔자, [키워드] 3D8 scFv antivirus H1N1/H275Y prophylactic effect therapeutic effect. [DOI] 10.3390/v14051105 PMC 바로가기
Anti-SARS-CoV-2 potential of Cissampelos pareira L. identified by connectivity map-based analysis and in vitro studiesResearch Published on 2022-04-222023-07-01 Journal: BMC Complementary Medicine and Therapies [Category] COVID19(2023년), SARS, [키워드] Cissampelos pareira L. antivirus BALF Connectivity map COVID-19 SARS-CoV-2 Whole plant extract [DOI] 10.1186/s12906-022-03584-3 PMC 바로가기 [Article Type] Research
A Defective Viral Particle Approach to COVID-19Review Published on 2022-01-172022-10-31 Journal: Cells [Category] COVID-19, SARS, [키워드] adaptive antivirus aptamer caused coronavirus Coronaviruses COVID-19 death Defective Interfering Particle DIP extracellular vesicle function identify Immunity implementation Infection Intention knowledge Mutation novel coronavirus SARS-CoV-2 pandemic Particle resulting SARS-CoV-2 synthetic defective viral genome target therapeutic therapy vaccination Vaccine while [DOI] 10.3390/cells11020302 PMC 바로가기 [Article Type] Review
Metal-Protein Nanoparticles Facilitate Anti-VSV and H1N1 Viruses Through the Coordinative Actions on Innate Immune Responses and METTL14Article Published on 2021-04-012023-06-24 Journal: Macromolecular bioscience [Category] 신종인플루엔자, [키워드] antivirus innate immune responses m6A metal-protein nanoparticle. METTL14 , N6-methyladenosine [DOI] 10.1002/mabi.202000382 PMC 바로가기
Comprehensive Landscape of Heparin Therapy for COVID-19COVID-19에 대한 헤파린 요법의 종합적인 전망Review Published on 2021-02-152022-09-11 Journal: Carbohydrate polymers [Category] SARS, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition administration adverse effect adverse effects Anti-inflammation Anti-inflammatory Anticoagulant anticoagulant agent anticoagulation antiviral activities antivirus binding biochemical caused cells clinical clinical observation clinical observations Comprehensive concerning coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 disease Effect Effectiveness Evidence heparin in vitro study Infection landscape observation pandemic coronavirus pharmacological mechanism Protein public health emergency pulmonary thrombosis respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2. severe acute respiratory syndrome Coronavirus Spike protein systemic symptom systemic symptoms the Spike therapy thrombosis Viral viral infection [DOI] 10.1016/j.carbpol.2020.117232 PMC 바로가기 [Article Type] Review
Ivermectin: An Anthelmintic, an Insecticide, and Much MoreReview Published on 2021-01-012023-07-12 Journal: Trends in parasitology [Category] SARS, [키워드] Anthelmintic anticancer antimalaria antivirus insecticide ivermectin. [DOI] 10.1016/j.pt.2020.10.005 PMC 바로가기 [Article Type] Review